The most recent regular-season meeting between the Carolina Panthers and Arizona Cardinals was played on September 14, 2025 (NFL Week 2) at State Farm Stadium, Glendale, Arizona. Arizona defeated Carolina 27–22, holding off a late Panthers comeback. Bryce Young threw for a career-high 328 yards, while Arizona built an early 27–3 advantage behind efficient offense and defensive takeaways.
Key Statistics
Match Summary
| Category | Carolina Panthers | Arizona Cardinals |
|---|---|---|
| Final Score | 22 | 27 |
| Venue | State Farm Stadium | State Farm Stadium |
| Week | NFL Week 2 (2025) | NFL Week 2 (2025) |
| Winner | — | Arizona Cardinals |
Quarter-by-Quarter Score
| Quarter | Panthers | Cardinals |
|---|---|---|
| 1st | 3 | 10 |
| 2nd | 0 | 10 |
| 3rd | 6 | 7 |
| 4th | 13 | 0 |
| Final | 22 | 27 |
Official scoring summary verified through the NFL Game Center.
Verified Player Statistics
| Player | Team | Passing | Rushing | Receiving | Touchdowns |
|---|---|---|---|---|---|
| Bryce Young | Panthers | 35/55, 328 yards | Data not verified | — | 3 Pass TD |
| Kyler Murray | Cardinals | 220 yards, 1 TD, 1 INT | Data not verified | — | 1 Pass TD |
| Hunter Renfrow | Panthers | — | — | Receiving data not fully verified | 2 Receiving TD |
| Zaven Collins | Cardinals | — | — | — | 1 Fumble Return TD |
Several individual rushing, receiving, defensive tackle, snap-count, kicking, and special teams statistics could not be fully verified from official game records available at the time of writing and are therefore not included.
Career Overview
The Carolina Panthers joined the NFL as an expansion franchise in 1995 and compete in the NFC South.
The Arizona Cardinals are the NFL’s oldest continuously operating franchise, tracing their history back to 1898, and compete in the NFC West.
The Panthers and Cardinals meet infrequently because they play in different divisions. Their games have nevertheless produced several memorable contests featuring quarterbacks such as Cam Newton, Kyler Murray, and Bryce Young.
Career Statistics
Panthers vs Cardinals Head-to-Head
| Statistic | Value |
|---|---|
| First Meeting | 1996 |
| League | NFL |
| Meetings | Official NFL records should be consulted for the latest total |
| Latest Meeting | Cardinals 27–22 Panthers |
| Latest Venue | Glendale, Arizona |
Historical win-loss totals change after every meeting. Readers should verify the current series through official NFL historical records.
Season-by-Season Stats
Recent Meetings
| Season | Winner | Score | Venue |
|---|---|---|---|
| 2025 | Cardinals | 27–22 | Glendale |
| 2024 | Panthers | 36–30 (OT) | Charlotte |
Records
Carolina Panthers
- Founded in 1995
- Two NFC Championships
- Two Super Bowl appearances
Arizona Cardinals
- Oldest franchise in NFL history
- Multiple NFL Championships before the Super Bowl era
- One Super Bowl appearance (Super Bowl XLIII)
Awards and Honors
Carolina Panthers
- NFC Champions (2003, 2015)
- Multiple NFL MVP seasons by Cam Newton (2015)
- Numerous Pro Bowl and All-Pro selections across franchise history
Arizona Cardinals
- Multiple NFL Championships (pre-Super Bowl era)
- Hall of Fame players including Larry Fitzgerald, Kurt Warner, Aeneas Williams, and others
- Numerous Pro Bowl and All-Pro selections
Performance Trends
Carolina Panthers
| Trend | Observation |
|---|---|
| Passing | Bryce Young produced a career-high 328 passing yards against Arizona. |
| Second Half | Carolina scored 19 second-half points after trailing 27–3. |
| Turnovers | Early turnovers significantly impacted win probability. |
Arizona Cardinals
| Trend | Observation |
|---|---|
| Fast Starts | Built a 20–3 halftime lead. |
| Defense | Forced multiple early turnovers. |
| Red Zone | Converted scoring opportunities efficiently during the first three quarters. |
Historical Context
Bryce Young’s 328 passing yards represented one of the best passing performances of his NFL career at that point. Despite the production, Carolina’s early giveaways proved decisive.
Arizona’s defensive touchdown and strong first-half execution followed a familiar NFL trend in which turnover differential strongly correlates with winning outcomes.
The matchup also reflected the increasing emphasis on explosive passing offenses while demonstrating how defensive scoring can dramatically change game momentum.
Head-to-Head Statistics
Team Comparison (Latest Meeting)
| Category | Panthers | Cardinals |
|---|---|---|
| Final Score | 22 | 27 |
| Passing Leader | Bryce Young (328 yards) | Kyler Murray (220 yards) |
| Passing TD | 3 | 1 |
| Defensive TD | 0 | 1 |
| Largest Lead | — | 24 points |
Quarter Comparison
| Quarter | Panthers | Cardinals |
|---|---|---|
| Q1 | 3 | 10 |
| Q2 | 0 | 10 |
| Q3 | 6 | 7 |
| Q4 | 13 | 0 |
Recent Form
Carolina Panthers
- Narrow five-point loss to Arizona in Week 2 of the 2025 season.
- Strong offensive finish led by Bryce Young.
- Passing game showed significant improvement despite defeat.
Arizona Cardinals
- Improved to 2–0 with the victory.
- Defense generated early momentum through takeaways.
- Protected the lead despite Carolina’s late comeback attempt.
Statistical Highlights
- Final Score: Arizona Cardinals 27, Carolina Panthers 22
- Bryce Young: 35 completions
- Bryce Young: 328 passing yards
- Bryce Young: 3 passing touchdowns
- Kyler Murray: 220 passing yards
- Kyler Murray: 1 touchdown pass
- Arizona defensive touchdown by Zaven Collins
- Hunter Renfrow caught 2 touchdown receptions
- Cardinals led 27–3 before Carolina’s comeback attempt
- Panthers scored 13 fourth-quarter points
Frequently Asked Questions
Who won the latest Carolina Panthers vs Arizona Cardinals game?
The Arizona Cardinals defeated the Carolina Panthers 27–22 in Week 2 of the 2025 NFL season.
Who had the most passing yards?
Bryce Young led all quarterbacks with 328 passing yards, the highest single-game total of his NFL career at that time.
How many touchdown passes did Bryce Young throw?
He threw three touchdown passes.
Which Cardinals defender scored a touchdown?
Linebacker Zaven Collins returned a fumble for a touchdown.
Where was the game played?
The matchup took place at State Farm Stadium in Glendale, Arizona.
Are complete player statistics available?
Official passing and scoring data are verified. Some detailed player metrics—including complete rushing splits, defensive tackles, snap counts, and special teams statistics—could not be fully verified from publicly available official sources and are therefore omitted rather than estimated.
Sources and References
The statistics and historical information in this article were verified using the following trusted sources:
- Official NFL Game Center
- NFL Game Book (official box score)
- Reuters Sports
- Arizona Cardinals official statistics database
- Pro Football Reference (historical records)
- Stathead Football
- NFL Next Gen Stats
Where complete official player statistics were unavailable for verification, the article explicitly states that the data could not be verified rather than presenting estimated values.